Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1992 Mar 15;69(6 Suppl):1607-32.
doi: 10.1002/1097-0142(19920315)69:6+<1607::aid-cncr2820691317>3.0.co;2-c.

Selection of appropriate cellular and molecular biologic diagnostic tests in the evaluation of cancer

C M Fenoglio-Preiser  1
Affiliations
Review

Selection of appropriate cellular and molecular biologic diagnostic tests in the evaluation of cancer

C M Fenoglio-Preiser. Cancer. .

Abstract

In this article, the use of cellular and molecular markers to diagnose and stage tumors is discussed. Their role in the evaluation of tumor prognosis and tumor susceptibility also is covered. The immunologic, cytogenetic, and molecular phenotype is discussed. Traditional markers are compared with newer methodologic approaches including evaluation of oncogenes, tumor suppressor genes, and genes that predict tumor susceptibility. These discussions are presented in relation to specific tumors. Finally, statements one might use to decide which tests to perform are presented.

PubMed Disclaimer