Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 Jan;37(1):14-8.

Reduction of urinary oxalate by combined calcium and citrate administration without increase in urinary calcium oxalate stone formers

H Ito  1 , F Suzuki, K Yamaguchi, Y Nishikawa, T Kotake
Affiliations
  • PMID: 1541059

Reduction of urinary oxalate by combined calcium and citrate administration without increase in urinary calcium oxalate stone formers

H Ito et al. Clin Nephrol. 1992 Jan.

Abstract

Oxalic acid seems to play a far greater role in the formation of calcium oxalate stone than calcium. Three grams of calcium lactate and 3 g of sodium potassium citrate were administered to 46 urolithiasis patients, whose stones were mainly composed of calcium oxalate. Urinary oxalate level was reduced significantly without raising urinary calcium level by the administration of the two drugs for two weeks. The reduction of urinary oxalic acid was particularly remarkable in patients without hypercalciuria. The mechanism of action of these drugs was discussed.

PubMed Disclaimer

MeSH terms