Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Mar;22(3):215-8.
doi: 10.1002/art.1780220302.

Long term effectiveness of low dose mithramycin for Paget's disease of bone

A S Russell, I M Chalmers, J S Percy, B C Lentle

Long term effectiveness of low dose mithramycin for Paget's disease of bone

A S Russell et al. Arthritis Rheum. 1979 Mar.

Abstract

Nineteen patients with Paget's disease of bone were studied 7 months to 5 years after therapy with mithramycin in a dose averaging 11.5 microgram/kg body weight daily for 10 days. Thirteen patients, including 3 with the longest followup intervals, remained free of pain. Objective measures of disease activity (serum alkaline phosphatase level and 99mtechnetium pyrophosphate bone scan) were less favorable. There was no evidence of long term toxicity.

PubMed Disclaimer

LinkOut - more resources