Comment
doi: 10.1016/j.cell.2004.09.024.
Neuronal differentiation: TOR and insulin receptor pathways set the tempo
Affiliations
- PMID: 15454075
- DOI: 10.1016/j.cell.2004.09.024
Item in Clipboard
Comment
Neuronal differentiation: TOR and insulin receptor pathways set the tempo
Cell.
.
Free article
Abstract
Target of rapamycin (TOR) and insulin receptor pathways regulate growth in metazoans. A recent study reveals a novel role for these pathways in controlling the timing of neuronal differentiation during Drosophila development, thus allowing a tight coordination between growth and differentiation programs.
Comment on
-
Temporal control of differentiation by the insulin receptor/tor pathway in Drosophila.Cell. 2004 Oct 1;119(1):87-96. doi: 10.1016/j.cell.2004.08.028. Cell. 2004. PMID: 15454083
Similar articles
-
Temporal control of differentiation by the insulin receptor/tor pathway in Drosophila.Cell. 2004 Oct 1;119(1):87-96. doi: 10.1016/j.cell.2004.08.028. Cell. 2004. PMID: 15454083
-
Regulation of neurogenesis and epidermal growth factor receptor signaling by the insulin receptor/target of rapamycin pathway in Drosophila.Genetics. 2008 Jun;179(2):843-53. doi: 10.1534/genetics.107.083097. Epub 2008 May 27. Genetics. 2008. PMID: 18505882 Free PMC article.
-
Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome.Mol Syst Biol. 2011 Nov 8;7:547. doi: 10.1038/msb.2011.79. Mol Syst Biol. 2011. PMID: 22068330 Free PMC article.
-
TOR signaling: an odyssey from cellular stress to the cell growth machinery.Curr Biol. 2005 Feb 22;15(4):R139-41. doi: 10.1016/j.cub.2005.02.015. Curr Biol. 2005. PMID: 15723787 Review.
-
Drosophila aging 2005/06.Exp Gerontol. 2006 Dec;41(12):1213-6. doi: 10.1016/j.exger.2006.10.013. Epub 2006 Nov 28. Exp Gerontol. 2006. PMID: 17126511 Free PMC article. Review.
Cited by
-
Insulin in the brain: sources, localization and functions.Mol Neurobiol. 2013 Feb;47(1):145-71. doi: 10.1007/s12035-012-8339-9. Epub 2012 Sep 7. Mol Neurobiol. 2013. PMID: 22956272 Review.
-
Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's disease.Front Endocrinol (Lausanne). 2014 Oct 9;5:161. doi: 10.3389/fendo.2014.00161. eCollection 2014. Front Endocrinol (Lausanne). 2014. PMID: 25346723 Free PMC article. Review.
-
Continued neurogenesis in adult Drosophila as a mechanism for recruiting environmental cue-dependent variants.PLoS One. 2008 Jun 11;3(6):e2395. doi: 10.1371/journal.pone.0002395. PLoS One. 2008. PMID: 18545694 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
