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Comparative Study
. 1992 Jan;42(1):9-10.

Role of ciprofloxacin in typhoid fever

M A Akhtar  1 , A Hussain, K A Karamat, N Naqi, N Zubdi
Affiliations
  • PMID: 1545485
Comparative Study

Role of ciprofloxacin in typhoid fever

M A Akhtar et al. J Pak Med Assoc. 1992 Jan.

Abstract

A study was conducted to investigate the effects of ciprofloxacin in typhoid fever and to compare its efficacy with chloramphenicol. Eighty patients between 20-45 years with positive blood culture were included in the study. Seventy five percent patients treated with ciprofloxacin became afebrile within 72 hours while with chloramphenicol it took upto 120-144 hours for the same percentage of patients to become afebrile. Four patients resistant to chloramphenicol, cotrimoxazole and ampicillin/amoxycillin, also responded to ciprofloxacin. There were no significant adverse effects indicating that ciprofloxacin is safe and effective drug for resistant and nonresistant cases of typhoid fever.

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