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Comparative Study
. 1978 Sep;49(3):179-82.

The effect of germfree and SPF maintenance conditions on the lifespan and diseases of small laboratory animals

  • PMID: 154573
Comparative Study

The effect of germfree and SPF maintenance conditions on the lifespan and diseases of small laboratory animals

F Deerberg et al. J S Afr Vet Assoc. 1978 Sep.

Abstract

The mortality rates and spontaneous diseases defining the course of natural mortality graphs in colonies of Han: NMRI mice kept under conventional, SPF and germfree maintenance conditions are reported. A specific problem in SPF colonies is caused by ubiquitous germs. The lesions and possible reasons for such types of infections are discussed.

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