Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2004 Sep:18 Suppl B:3B-8B.
doi: 10.1155/2004/238037.

Gastrointestinal stromal tumours: etiology, pathology and clinical management

Martin E Blackstein  1 , Pierre Dubé, Jonathan A Fletcher, Oliver R Keller, Margaret Knowling, Richard Létourneau, Donald Morris, Robert Riddell, Stewart Rorke, Carol J Swallow; Canadian Advisory Committee on GIST
Collaborators, Affiliations
Review

Gastrointestinal stromal tumours: etiology, pathology and clinical management

Martin E Blackstein et al. Can J Gastroenterol. 2004 Sep.

Abstract

Investigation of the regulation of cell growth, differentiation and death by signalling pathways has led to a greater understanding of how alterations in these pathways play a critical role in the development of some cancers, and has opened new opportunities for their treatment. In the present review, results with the prototype drug of this class, imatinib (Gleevec, Glivec [formerly STI571]; Novartis, Switzerland), in metastatic gastrointestinal stromal tumours are presented. The present review originated from a conference of the authors held in Montreal, Quebec in June 2003, under the sponsorship of Novartis.

PubMed Disclaimer

MeSH terms