Predictors of quality of life among long-term survivors of gestational trophoblastic disease

Abstract

Objective: To identify predictors of quality of life (QOL) among women diagnosed with gestational trophoblastic tumor (GTT) 5-10 years earlier.

Study design: Utilizing a cross-sectional, descriptive design, 111 survivors completed a comprehensive QOL interview.

Results: Univariate analyses revealed that numerous psychosocial variables correlated highly with overall QOL. However, multivariate analysis indicated that the significant predictors of long-term QOL were cancer-specific distress, social support, spiritual well-being, reproductive concerns, gynecologic pain and sexual functioning. These 6 variables accounted for 77% of the variance in the overall QOL score. Post hoc analyses demonstrated that each of the predictors had unique effects on the QOL score.

Conclusion: The variables identified in this model can guide future research and clinical care to reduce short- and long-term burdens associated with GTT.