Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Oct;114(7):872-6.
doi: 10.1172/JCI23245.

From progress to regression: biomedical research funding

H George Mandel  1 , Elliot S Vesell
Affiliations

From progress to regression: biomedical research funding

H George Mandel et al. J Clin Invest. 2004 Oct.

Erratum in

  • J Clin Invest. 2004 Dec;114(11):1687

Abstract

Despite great advances in health-related research and health care, major challenges remain regarding the causes and cures of many diseases; these may be overcome with further research. Our society is enthusiastic about fostering such investigations. However, available federal funds limit many such projects. Previously there have been sizable increases in the NIH budget, but because of the escalating cost of scientific investigation and the pressures of financing other much-needed governmental programs, recent growth in biomedical research funding has barely kept up with inflation. This article focuses on select attempts to sustain the record of scientific achievement enabled in the past by continued increasing investment and also suggests some solutions.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Success rates of funded R01 applications, new and renewals (orange and blue bars, respectively) by FY. Line, total annual NIH budget allocation, in billions of dollars.
Figure 2
Figure 2
Total number of new (orange bars) and renewal (blue bars) R01 applications submitted to the NIH for review, by FY.
See this image and copyright information in PMC

References

    1. Lederman LM. The advancement of science (1992) Science. 1992;256:1119–1124. - PubMed
    1. National Science Board. 2004. Science and Engineering Indicators 2004. Volume 1, NSB 04-1; Volume 2, NSB 04-1A. http://www.nsf.gov/sbe/srs/seind04/start.htm.
    1. Pardes H, et al. Effects of medical research on health care and the economy. Science. 1999;283:36–37. - PubMed
    1. NIH. 2004. The NIH almanac — appropriations, Section 2. http://www.nih.gov/about/almanac/index.html.
    1. NIH. 2004. Summary of the FY 2005 president’s budget. http://www.nih.gov/about/director/budgetrequest/index.htm.