Erythropoietin in the critically ill - is it more than just blood?
- PMID: 15469592
- PMCID: PMC1065033
- DOI: 10.1186/cc2949
Erythropoietin in the critically ill - is it more than just blood?
Abstract
Erythropoietin (EPO) has been in clinical use for the treatment of anemia for over 15 years. Recently it has been demonstrated that EPO has actions other than stimulating the bone marrow. It has been suggested that due to its tissue protecting effect, EPO may be effective in improving outcome in the critically ill.
Comment on
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Science review: recombinant human erythropoietin in critical illness: a role beyond anemia?Crit Care. 2004 Oct;8(5):337-41. doi: 10.1186/cc2897. Epub 2004 Jun 16. Crit Care. 2004. PMID: 15469595 Free PMC article. Review.
References
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- Erbayraktar S, Yilmaz O, Gokmen N, Brines M. Erythropoietin is a multifactorial tissue-protective cytokine. Curr Hematol Rep. 2003;2:465–470. - PubMed
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- Silverberg DS, Wexler D, Blum M, Keren G, Sheps D, Leibovitch E, Brosh D, Laniado S, Schwartz D, Yachnin T, et al. The use of subcutaneous erythropoietin intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac and renal function and functional cardiac class and markedly reduces hospitalization. J Am Coll Cardiol. 2000;35:1737–1744. doi: 10.1016/S0735-1097(00)00613-6. - DOI - PubMed
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