Comment
doi: 10.1016/j.devcel.2004.09.008.
Ena/VASP family: new partners, bigger enigma
Affiliations
- PMID: 15469834
- DOI: 10.1016/j.devcel.2004.09.008
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Comment
Ena/VASP family: new partners, bigger enigma
Dev Cell.
2004 Oct.
Free article
Abstract
Linking external signals to remodeling of the cytoskeleton is essential to multiple processes during animal development and physiology. Two new studies have uncovered a new family of proteins that can regulate actin dynamics both locally at the membrane interface and globally throughout the cell.
Comment on
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Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics.Dev Cell. 2004 Oct;7(4):571-83. doi: 10.1016/j.devcel.2004.07.024. Dev Cell. 2004. PMID: 15469845
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RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion.Dev Cell. 2004 Oct;7(4):585-95. doi: 10.1016/j.devcel.2004.07.021. Dev Cell. 2004. PMID: 15469846
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