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Review
. 2004 Sep;5(3):185-96.
doi: 10.1023/b:prev.0000037641.26017.00.

A conceptual framework for adaptive preventive interventions

Linda M Collins  1 , Susan A Murphy, Karen L Bierman
Affiliations
Review

A conceptual framework for adaptive preventive interventions

Linda M Collins et al. Prev Sci. 2004 Sep.

Abstract

Recently, adaptive interventions have emerged as a new perspective on prevention and treatment. Adaptive interventions resemble clinical practice in that different dosages of certain prevention or treatment components are assigned to different individuals, and/or within individuals across time, with dosage varying in response to the intervention needs of individuals. To determine intervention need and thus assign dosage, adaptive interventions use prespecified decision rules based on each participant's values on key characteristics, called tailoring variables. In this paper, we offer a conceptual framework for adaptive interventions, discuss principles underlying the design and evaluation of such interventions, and review some areas where additional research is needed.

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References

    1. Bather JA. Decision theory: An introduction to dynamic programming and sequential decisions. Wiley; New York: 2000.
    1. Bertsekas DP, Tsitsiklis JN. Neuro-dynamic programming. Athena Scientific; Belmont, MA: 1996.
    1. Bierman KL, Nix RL, Maples JJ, Murphy SA, Conduct Problems Prevention Research Group Evaluating the use of clinical judgment in the context of an adaptive intervention design: The Fast Track Prevention Program. 2004. Manuscript submitted for publication. - PMC - PubMed
    1. Borhani NO, Applegate WB, Cutler JA, Davis BR, Furberg CD, Lakatos E, Page L, Perry HM, Smith WM, Probstfield JL. Systolic hypertension in the elderly program (SHEP). Part 1: Rationale and design. Hypertension. 1991;17(Suppl II):2–15. - PubMed
    1. Breslin F, Sobell MB, Sobell LC, Buchan G, Cunningham JA. Toward a stepped care approach to treating problem drinkers: The predictive utility of within-treatment variables and therapist prognostic ratings. Addiction. 1997;92:1479–1489. - PubMed

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