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. 1992 Mar 6;68(5):989-94.
doi: 10.1016/0092-8674(92)90041-a.

Requirement for E. coli NusG protein in factor-dependent transcription termination

S L Sullivan  1 , M E Gottesman
Affiliations

Requirement for E. coli NusG protein in factor-dependent transcription termination

S L Sullivan et al. Cell. .

Abstract

The 21 kd NusG protein is essential for E. coli viability. Cells depleted for NusG were defective for factor-dependent transcription termination. Rho-induced polarity in the gal operon and the Rho-dependent lambda tR1 and lambda tL1 terminators were suppressed in NusG-deficient cells. NusG depletion inactivated the phage HK022 Nun termination factor. In contrast, the factor-independent lambda tl terminator was fully active in NusG-depleted cells and could be suppressed by phage lambda N function.

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