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. 2004 Dec;28(12):1273-80.
doi: 10.1016/j.leukres.2004.04.008.

Histopathologic verification of acute leukemia (AL) in a cohort of 463 post-Chernobyl patients from Belarus, Russia and Ukraine

Philip L McCarthy Jr  1 , Ora Paltiel, Elena Maslova, Sergei Kulikov, Theresa Hahn, Kenneth J Kopecky, Vera Drozdova, Natalya Shmatina, Ludmilla Tichonova, Jack Van Hoff, Inna Gavrilova, Howard Weinstein
Affiliations

Histopathologic verification of acute leukemia (AL) in a cohort of 463 post-Chernobyl patients from Belarus, Russia and Ukraine

Philip L McCarthy Jr et al. Leuk Res. 2004 Dec.

Abstract

Seven morphologists examined 382 slide and 82 non-slide, post-Chernobyl pediatric acute leukemia (AL) cases in radiation-exposed areas of Belarus, Russia and Ukraine; part of a case-control study by the International Consortium for Research on the Health Effects of Radiation. Among the slide cases, 99% were confirmed as AL: 92% acute lymphoid leukemia (ALL) and 86% acute myeloid leukemia (AMD demonstrating the utility of FAB classification for distinguishing ALL and AML. Among the non-slide cases, 79% were confirmed as AL: 84% ALL, and 71% AML. This study affirms AL diagnostic accuracy during a time of social upheaval in the former Soviet Union.

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