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. 2005 Feb;150(2):371-7.
doi: 10.1007/s00705-004-0401-0. Epub 2004 Oct 11.

Genetic diversity of sapovirus in fecal specimens from infants and children with acute gastroenteritis in Pakistan

T G Phan  1 , M Okame, T A Nguyen, O Nishio, S Okitsu, H Ushijima
Affiliations

Genetic diversity of sapovirus in fecal specimens from infants and children with acute gastroenteritis in Pakistan

T G Phan et al. Arch Virol. 2005 Feb.

Abstract

A total of 517 fecal specimens collected from infants and children with acute gastroenteritis in Karachi city, Pakistan during 1990-1994 were examined for the presence of sapovirus by RT-PCR and sequence analysis methods. Sapovirus was identified in 17 of 517 (3.2%) specimens. Sapovirus was further clustered into three distinct genogroups (I, II and IV) and these presented 70.6%, 23.5% and 5.9%, respectively. Our results clearly indicated that sapovirus could be classified into 7 GI and 4 GII genotypes. It was noteworthy to point out that sapovirus detected among Pakistani infants and children with acute gastroenteritis demonstrated the great genetic diversity and presented novel sapovirus genotypes.

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