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. 2004 Dec;214(12):606-14.
doi: 10.1007/s00427-004-0441-1. Epub 2004 Oct 14.

Organization of the Hox gene cluster of the silkworm, Bombyx mori: a split of the Hox cluster in a non-Drosophila insect

Yuji Yasukochi  1 , Laksmikutty A Ashakumary, Chengcang Wu, Atsuo Yoshido, Junko Nohata, Kazuei Mita, Ken Sahara
Affiliations

Organization of the Hox gene cluster of the silkworm, Bombyx mori: a split of the Hox cluster in a non-Drosophila insect

Yuji Yasukochi et al. Dev Genes Evol. 2004 Dec.

Abstract

A bacterial artificial chromosome (BAC) contig was constructed by chromosome walking, starting from the Hox genes of the silkworm, Bombyx mori. Bombyx orthologues of the labial (lab) and zerknult (zen) genes were newly identified. The size of the BAC contig containing the Hox gene cluster-except the lab and Hox 2 genes-was estimated to be more than 2 Mb. The Bombyx Hox cluster was mapped to linkage group (LG) 6. The lab gene was mapped on the same LG, but far apart from the cluster. Fluorescence in situ hybridization analysis confirmed that the major Hox gene cluster and lab were at different locations on the same chromosome in B. mori.

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