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. 2004 Nov 1;39(9):1380-4.
doi: 10.1086/424883. Epub 2004 Oct 11.

Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002

Roger Bedimo  1 , Ray Y Chen, Neil A Accortt, James L Raper, Carol Linn, Jeroan J Allison, John Dubay, Michael S Saag, Craig J Hoesley
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Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002

Roger Bedimo et al. Clin Infect Dis. .

Abstract

In a comparison of rates of acquired immunodeficiency syndrome (AIDS)-defining malignancies (ADMs) for 1989-1996 versus 1997-2002, we found a decrease in ADMs (rate ratio, 0.31; P<.0001) and a significant increase in non-AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P<.0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration of survival during highly active antiretroviral therapy might explain the increasing incidence of non-ADMs.

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