tRNA maturation: RNA polymerization without a nucleic acid template
- PMID: 15498478
- DOI: 10.1016/j.cub.2004.09.069
tRNA maturation: RNA polymerization without a nucleic acid template
Abstract
The CCA-adding enzyme, which builds and repairs the 3' terminal CCA sequence of tRNA, is the only RNA polymerase that can synthesize a defined nucleotide sequence without using a nucleic acid template. New cocrystal structures tell us how this remarkable enzyme works.
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