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Review
. 2004 Oct 26;14(20):R883-5.
doi: 10.1016/j.cub.2004.09.069.

tRNA maturation: RNA polymerization without a nucleic acid template

Alan M Weiner  1
Affiliations
Free article
Review

tRNA maturation: RNA polymerization without a nucleic acid template

Alan M Weiner. Curr Biol. .
Free article

Abstract

The CCA-adding enzyme, which builds and repairs the 3' terminal CCA sequence of tRNA, is the only RNA polymerase that can synthesize a defined nucleotide sequence without using a nucleic acid template. New cocrystal structures tell us how this remarkable enzyme works.

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