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. 2003 Dec;136(6):554-6.
doi: 10.1023/b:bebm.0000020201.51742.28.

Megakaryocytopoiesis under hypoxic conditions

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Megakaryocytopoiesis under hypoxic conditions

E V Lebedeva et al. Bull Exp Biol Med. 2003 Dec.

Abstract

Acute and chronic hypoxia led to acceleration of proliferation and differentiation of bone marrow megakaryocytes and increase in their functional activity. The count of young cells in the peripheral blood increased during acute hypoxia. Chronic hypoxia led to increase in the number of old platelets with lower functional activity, which was accompanied by thrombocytosis.

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