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Case Reports
. 2004 Nov;25(11):826-8.
doi: 10.1016/j.revmed.2004.07.008.

[Hemophagocytic syndrome complicating adult's seropositive rheumatoid arthritis]

[Article in French]
A Niang  1 , S Diallo, M M Ka, A Pouye, S Diop, S Ndongo, T M Diop
Affiliations
Case Reports

[Hemophagocytic syndrome complicating adult's seropositive rheumatoid arthritis]

[Article in French]
A Niang et al. Rev Med Interne. 2004 Nov.

Abstract

Introduction: Macrophage activation syndrome (MAS) is a severe complication of chronic rheumatic diseases, particularly juvenile rheumatoid arthritis. However, MAS is rarely described in adult rheumatoid polyarthritis.

Exegese: We report a case of MAS complicating a seropositive rheumatoid polyarthritis after 20 years of evolution. Pancytopenia with fever, renal failure and hepatic dysfunction revealed the disease that was confirmed by multiple macrophages and monocytes invading the bone marrow specimen.

Conclusion: Outcome has been spectacular under corticosteroids.

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