doi: 10.1212/01.wnl.0000142258.29304.fe.
PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations
Affiliations
- PMID: 15505170
- DOI: 10.1212/01.wnl.0000142258.29304.fe
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PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations
Neurology.
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Abstract
The authors performed linkage analysis in 39 families with autosomal recessive early-onset PD (AR-EOPD) negative for parkin and DJ-1 mutations. Eight families including three Japanese, two Taiwanese, one Turkish, one Israeli, and one Philippine showed evidence of linkage with PARK6 with multipoint log of the odds (lod) score of 9.88 at D1S2732. The results indicate worldwide distribution of PARK6-linked parkinsonism.
Comment in
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What does PINK1 mean for Parkinson diseases?Neurology. 2004 Oct 26;63(8):1350-1. doi: 10.1212/01.wnl.0000144272.53634.49. Neurology. 2004. PMID: 15505146 No abstract available.
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