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. 2004 Oct 26;63(8):1482-5.
doi: 10.1212/01.wnl.0000142258.29304.fe.

PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations

Y Hatano  1 , K Sato, B Elibol, H Yoshino, Y Yamamura, V Bonifati, H Shinotoh, M Asahina, S Kobayashi, A R Ng, R L Rosales, S Hassin-Baer, Y Shinar, C S Lu, H C Chang, Y H Wu-Chou, F B Ataç, T Kobayashi, T Toda, Y Mizuno, N Hattori
Affiliations

PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations

Y Hatano et al. Neurology. .

Abstract

The authors performed linkage analysis in 39 families with autosomal recessive early-onset PD (AR-EOPD) negative for parkin and DJ-1 mutations. Eight families including three Japanese, two Taiwanese, one Turkish, one Israeli, and one Philippine showed evidence of linkage with PARK6 with multipoint log of the odds (lod) score of 9.88 at D1S2732. The results indicate worldwide distribution of PARK6-linked parkinsonism.

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