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. 2004 Sep;95(6):761-5.
doi: 10.5980/jpnjurol1989.95.761.

[A clinical study of estramustine phosphate sodium for the treatment of hot flushes in men with prostate cancer]

[Article in Japanese]
Shinichiro Fukuhara  1 , Shohei Yokoyama, Koichi Tsutahara, Naoki Mori, Tsuneo Hara, Seiji Yamaguchi
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Free article

[A clinical study of estramustine phosphate sodium for the treatment of hot flushes in men with prostate cancer]

[Article in Japanese]
Shinichiro Fukuhara et al. Nihon Hinyokika Gakkai Zasshi. 2004 Sep.
Free article

Abstract

Purpose: To assess the effectiveness and tolerability of estramustine sodium phosphate in men with hot flushes during combined androgen blockade (CAB) therapy for prostate cancer.

Patients and methods: Seven men with moderate to severe hot flushes were received estramustine sodium phosphate. Treatment response was assessed by hot flush score.

Results: A significant reduction in the hot flush score was seen with all patients. No thromboembolic complications occurred in any patients.

Conclusions: Estramustine sodium phosphate appears to be a promising, well-tolerated and useful therapy for men with hot flushes during CAB treatment for prostate cancer.

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