Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2004;36(10):771-2.
doi: 10.1080/00365540410020956.

Impact of prolonged treatment with trimethoprim-sulfamethoxazole on the human gut flora

Diamantis P Kofteridis  1 , Sofia Maraki, Ioanna Mixaki, Elpis Mantadakis, George Samonis
Affiliations
Case Reports

Impact of prolonged treatment with trimethoprim-sulfamethoxazole on the human gut flora

Diamantis P Kofteridis et al. Scand J Infect Dis. 2004.

Abstract

The case of a mentally ill man inadvertently treated with trimethoprim-sulfamethoxazole (TMP-SMX) for 2 y is presented. Quantitative stool cultures revealed a substantially suppressed Gram-negative aerobic flora, while Enterococcus spp. and anaerobes were not affected. Yeasts were moderately increased. TMP-SMX represents an attractive antimicrobial for immunocompromized patients who need the integrity of their intestinal anaerobic flora for colonization resistance.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources