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. 1992 Mar;88(6):653-7.
doi: 10.1007/BF02265292.

Assignment of the gene encoding the catalytic subunit C beta of cAMP-dependent protein kinase to the p36 band on chromosome 1

J Simard  1 , D Bérubé, M Sandberg, K H Grzeschik, R Gagné, V Hansson, T Jahnsen
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Assignment of the gene encoding the catalytic subunit C beta of cAMP-dependent protein kinase to the p36 band on chromosome 1

J Simard et al. Hum Genet. 1992 Mar.

Abstract

A cDNA for the human catalytic subunit (C beta) of cAMP-dependent protein kinase (PKA) has been cloned from a testis cDNA library. In the present study, we have determined the chromosomal localization of this gene using a cDNA for C beta as a probe. Southern blot analysis of genomic DNA from human/mouse cell hybrids revealed that the presence or absence of a 20-kb XbaI fragment, which hybridized with the C beta probe, was concordant with the presence of human chromosome 1. In situ hybridization to metaphase chromosome confirmed the somatic cell hybrid data and regionally mapped the C beta gene of PKA to the p36 band on chromosome 1.

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References

    1. Somatic Cell Genet. 1976 Sep;2(5):401-10 - PubMed
    1. J Biol Chem. 1986 Dec 15;261(35):16288-91 - PubMed
    1. J Biol Chem. 1986 Nov 25;261(33):15360-3 - PubMed
    1. Proc Natl Acad Sci U S A. 1983 Jun;80(12):3608-12 - PubMed
    1. Cancer Res. 1985 Apr;45(4):1823-7 - PubMed

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