Infection prophylaxis of gunshot wounds using probiotics

Abstract

Objective: To report a new method of surgical infection prophylaxis for postoperative gunshot wounds to the extremities.

Method: Gunshot wounded animals were divided into three groups: treatment (probiotic Sporobacterin), antibiotic (cephalosporin cefamezin) and control (no treatment). Histological studies of wound-bed tissue were taken on days 1, 3, 5 and 10 of the study.

Results: The probiotic administered per os was more effective than antibiotics for prophylaxis of surgical infection.

Conclusion: The probiotic's effect is based on the natural defence mechanism activated after injury--the bacterial translocation of saprophytic bacteria from the gut to the wound.

Declaration of interest: None.