Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2004 Nov 15;23(1):91-6.
doi: 10.1016/j.vaccine.2004.03.067.

Does influenza vaccination exacerbate asthma in children?

Herman J Bueving  1 , Roos M D Bernsen, Johan C de Jongste, Lisette W A van Suijlekom-Smit, Guus F Rimmelzwaan, Albert D M E Osterhaus, Maureen P M H Rutten-van Mölken, Siep Thomas, Johannes C van der Wouden
Affiliations
Clinical Trial

Does influenza vaccination exacerbate asthma in children?

Herman J Bueving et al. Vaccine. .

Abstract

Background: The risks of influenza vaccination in asthmatic children are still being discussed. Especially, the risk that influenza vaccination may exacerbate asthma is an issue in this debate.

Methods: We conducted a randomised double-blind placebo-controlled trial in 696 children 6-18 years of age with asthma recruited in general practice during two influenza seasons, 1999-2000 and 2000-2001. Children participated for only one season. During the first week after vaccination, participants recorded local, influenza like and asthma symptoms as well as use of medication, health care use and absenteeism.

Results: Except for cough during the day in the first season, favouring placebo, there were no differences indicating that vaccination exacerbates asthma.

Conclusions: Influenza vaccination does not seem to exacerbate asthma.

PubMed Disclaimer

Publication types

Substances