Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2004 Dec;15(6):503-7.
doi: 10.1097/01.icu.0000143684.22362.46.

Ocular manifestations of graft versus host disease

Nicholas G Anderson  1 , Carl Regillo
Affiliations
Review

Ocular manifestations of graft versus host disease

Nicholas G Anderson et al. Curr Opin Ophthalmol. 2004 Dec.

Abstract

Purpose of review: A review of the current literature regarding the ocular manifestations and management of graft versus host disease is presented.

Recent findings: A variety of systemic and topical anti-inflammatory or immunomodulatory agents, including prednisolone acetate, cyclosporine A, FK506, autologous serum, and retinoic acid show promise in controlling ocular graft versus host disease.

Summary: Graft versus host disease is a common manifestation of allogeneic stem cell transplantation. Ocular manifestations are found in a majority of patients and may be the presenting symptom. Ocular findings include keratoconjunctivitis sicca, pseudomembranous conjunctivitis, corneal ulceration and perforation, and microvascular retinopathy. Systemic and local therapy may be used to control ocular disease.

PubMed Disclaimer

MeSH terms

Substances