Relation of left ventricular sphericity to 10-year survival after acute myocardial infarction

Abstract

After ST-elevation myocardial infarction, the association between left ventricular sphericity (measured by biplane ventriculography) and survival rate at a median of 6.5 years was determined in 825 patients. The highest tertile of sphericity (vs the lowest and middle tertiles) was associated with a decreased 10-year survival rate in patients who had anterior myocardial infarction (p = 0.002), inferior myocardial infarction (p = 0.011), Thrombolysis In Myocardial Infarction (TIMI) grade 3 flow (p = 0.005), or TIMI grade 0 to 2 flow (p = 0.001) in the infarct artery. The independent multivariate predictors of a 10-year survival rate were ejection fraction (p = 0.002), treadmill exercise duration (p = 0.004), biplane left ventricular sphericity index (p = 0.032), age (p = 0.043), and end-systolic volume index (p = 0.047), but not TIMI flow grade.