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. 2004 Dec;48(12):4926-8.
doi: 10.1128/AAC.48.12.4926-4928.2004.

Emergence in Asian countries of Staphylococcus aureus with reduced susceptibility to vancomycin

Jae-Hoon Song  1 , Keiichi Hiramatsu, Ji Yoeun Suh, Kwan Soo Ko, Teruyo Ito, Maria Kapi, Sungmin Kiem, Yeon-Sook Kim, Won Sup Oh, Kyong Ran Peck, Nam Yong Lee; Asian Network for Surveillance of Resistant Pathogens Study Group
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Emergence in Asian countries of Staphylococcus aureus with reduced susceptibility to vancomycin

Jae-Hoon Song et al. Antimicrob Agents Chemother. 2004 Dec.

Abstract

To investigate the prevalence of Staphylococcus aureus with reduced susceptibility to vancomycin among methicillin-resistant S. aureus (MRSA) strains in Asian countries, a total of 1,357 clinical isolates of MRSA collected from 12 Asian countries were screened by using brain heart infusion agar plates containing 4 mg of vancomycin per liter. The presence of strains that were heterointermediately resistant to vancomycin (hVISA) was confirmed by population analysis. Of 347 (25.6%) MRSA isolates that grew on the screening agar plates, 58 isolates (4.3%) were hVISA. hVISA strains were found in India, South Korea, Japan, the Philippines, Singapore, Thailand, and Vietnam. However, neither vancomycin-intermediate S. aureus nor vancomycin-resistant S. aureus isolates were found among MRSA isolates from Asian countries in this survey.

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Figures

FIG. 1.
FIG. 1.
Population analysis profile of hVISA strains from Asian countries. Two hVISA strains, Korea 116 and India 93, contained subpopulations that grew in the presence of a vancomycin concentration of 4 mg/liter at frequencies of ≥10−6.
See this image and copyright information in PMC

References

    1. Ariza, J., M. Pujol, C. Cabo, C. Peña, N. Fernándes, J. Liñares, J. Ayats, and F. Gudiol. 1999. Vancomycin in surgical infections due to methicillin-resistant Staphylococcal aureus with heterogeneous resistance to vancomycin. Lancet 353:1587-1588. - PubMed
    1. Bert, F., J. Clarissou, F. Durand, D. Delefosse, C. Chauvet, P. Lefebvre, N. Lambert, and C. Branger. 2003. Prevalence, molecular epidemiology, and clinical significance of heterogeneous glycopeptide-intermediate Staphylococcus aureus in liver transplant recipients. J. Clin. Microbiol. 41:5147-5152. - PMC - PubMed
    1. Bierbaum, G., K. Fuchs, W. Lenz, C. Szekat, and H. G. Sahl. 1999. Presence of Staphylococcus aureus with reduced susceptibility to vancomycin in Germany. Eur. J. Clin. Microbiol. Infect. Dis. 18:691-696. - PubMed
    1. Centers for Disease Control and Prevention. 2002. Staphylococcus aureus resistant to vancomycin—United States, 2002. Morb. Mortal. Wkly. Rep. 51:565-567. - PubMed
    1. Centers for Disease Control and Prevention. 2002. Vancomycin-resistant Staphylococcus aureus—Pennsylvania, 2002. Morb. Mortal. Wkly. Rep. 51:902. - PubMed

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