Review
doi: 10.1039/b316419p.
Epub 2004 Oct 28.
Biosynthesis of pantothenate
Affiliations
- PMID: 15565250
- DOI: 10.1039/b316419p
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Review
Biosynthesis of pantothenate
Nat Prod Rep.
2004 Dec.
Abstract
Pantothenate is an essential metabolite for all biological systems, however, the biosynthetic pathway is limited to plants, eubacteria and archaea. This suggests that the pathway is a strong candidate for the discovery of novel antibiotic and herbicidal compounds. The enzymology of this short pathway in both bacteria and plants is discussed in detail. In addition a short survey of studies of the whole pathway, and a discussion of both the metabolism and the transport of pantothenate are included.
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