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Case Reports
. 2005 Feb;24(1):83-6.
doi: 10.1007/s10067-004-0998-0. Epub 2004 Nov 24.

p-ANCA-associated periaortitis with histological proof of Wegener's granulomatosis: case report

T Carels  1 , E Verbeken, D Blockmans
Affiliations
Case Reports

p-ANCA-associated periaortitis with histological proof of Wegener's granulomatosis: case report

T Carels et al. Clin Rheumatol. 2005 Feb.

Abstract

We describe a 63-year-old man who presented with an inflammatory aortic aneurysm. The patient had p-ANCA antibodies directed against myeloperoxidase. A diagnosis of idiopathic periaortitis was made. Seven years later, he was rehospitalized because of fever, weight loss, and polyneuropathy. After revision of the aortic biopsy, which showed necrotizing vasculitis with palisading granuloma, a diagnosis of Wegener's granulomatosis (WG) was made. This case report illustrates an unusual disease course in WG, resembling large vessel vasculitis, and we discuss the possible mechanisms of large vessel involvement in this form of vasculitis.

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Comment in

  • ANCA-associated large vessel compromise.
    Chirinos JA, Corrales VF, Lichtstein DM. Chirinos JA, et al. Clin Rheumatol. 2006 Feb;25(1):111-2. doi: 10.1007/s10067-005-1139-0. Epub 2005 Jun 25. Clin Rheumatol. 2006. PMID: 15980936 No abstract available.

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