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. 2004 Dec;30(6):436-8.
doi: 10.1111/j.1447-0756.2004.00227.x.

Long-term serological outcome of infants who received frozen-thawed milk from human T-lymphotropic virus type-I positive mothers

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Long-term serological outcome of infants who received frozen-thawed milk from human T-lymphotropic virus type-I positive mothers

Yoshiya Ando et al. J Obstet Gynaecol Res. 2004 Dec.

Abstract

Aim: Human T-lymphotropic virus type-I (HTLV-I) infection occurs via mothers' milk during feeding. However, freeze-thaw processing can eliminate the infectivity of the mother's milk of HTLV-I carriers.

Methods: A long-term follow-up survey was conducted to investigate the HTLV-I infectivity of frozen-thawed mothers' milk among infants whose mothers were HTLV-I seropositive.

Results: Infants fed frozen-thawed mothers' milk did not become HTLV-I antibody-positive up until 1 year old, and all children followed up until an age of 11-12 years were antibody negative.

Conclusions: This study showed that freeze-thaw processing can eliminate the HTLV-I infectivity of mothers' milk, and that HTLV-I carriers can indirectly feed their infants using frozen-thawed mothers' milk as a way to prevent HTLV-I infection.

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