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. 2004 Nov;67(11):1783-8.
doi: 10.1021/np030530j.

Benzoic acid derivatives from Piper species and their fungitoxic activity against Cladosporium cladosporioides and C. sphaerospermum

João Henrique G Lago  1 , Clécio Sousa Ramos, Diego Campos C Casanova, Andreia de A Morandim, Debora Cristina B Bergamo, Alberto J Cavalheiro, Vanderlan da S Bolzani, Maysa Furlan, Elsie F Guimarães, Maria Claudia M Young, Massuo J Kato
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Benzoic acid derivatives from Piper species and their fungitoxic activity against Cladosporium cladosporioides and C. sphaerospermum

João Henrique G Lago et al. J Nat Prod. 2004 Nov.

Abstract

Piper crassinervium, P. aduncum, P. hostmannianum, and P. gaudichaudianum contain the new benzoic acid derivatives crassinervic acid (1), aduncumene (8), hostmaniane (18), and gaudichaudianic acid (20), respectively, as major secondary metabolites. Additionally, 19 known compounds such as benzoic acids, chromenes, and flavonoids were isolated and identified. The antifungal activity of these compounds was evaluated by bioautographic TLC assay against Cladosporium cladosporioides and C. sphaerospermum.

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