Case Reports
Abnormal fluid-attenuated inversion recovery signal foci in the splenium of a patient with presenilin-1 mutation
- PMID: 15569768
- PMCID: PMC8148752
Item in Clipboard
Case Reports
Abnormal fluid-attenuated inversion recovery signal foci in the splenium of a patient with presenilin-1 mutation
AJNR Am J Neuroradiol.
2004 Nov-Dec.
No abstract available
Figures
Suppression of ventricular fluid signal by using the FLAIR sequence unmasked the abnormality hidden by the conventional T2-weighted sequence. A, Axial FLAIR image, revealing a discrete thin band of signal intensity hyperintensity in the anterior subependymal region of the splenium. B, T2-weighted image, showing that CSF signal intensity obscured assessment of the anterior splenium (arrow).
Similar articles
-
Very early onset AD with a de novo mutation in the presenilin 1 gene (Met 233 Leu).Neurology. 2003 Oct 28;61(8):1136-7. doi: 10.1212/01.wnl.0000086811.39675.79. Neurology. 2003. PMID: 14581682
-
A presenilin-1 mutation in a Japanese family with Alzheimer's disease and distinctive abnormalities on cranial MRI.Neurology. 1997 Apr;48(4):1118-20. doi: 10.1212/wnl.48.4.1118. Neurology. 1997. PMID: 9109915
-
[Neuroradiological findings in Alzheimer dementia with the presenile mutation].Rofo. 1998 Jan;168(1):97-100. doi: 10.1055/s-2007-1015189. Rofo. 1998. PMID: 9501942 Review. German. No abstract available.
-
Focal lesion in the splenium of the corpus callosum on FLAIR MR images: a common finding with aging and after brain radiation therapy.AJNR Am J Neuroradiol. 2003 May;24(5):855-61. AJNR Am J Neuroradiol. 2003. PMID: 12748085 Free PMC article.
-
Presenilin mutations in Alzheimer's disease: molecular models suggest a potential functional locus.Trends Pharmacol Sci. 1996 Nov;17(11):389-93. doi: 10.1016/s0165-6147(96)40003-7. Trends Pharmacol Sci. 1996. PMID: 8990952 Review. No abstract available.
Cited by
-
Presenilin-1 mutation associated with amnesia, ataxia, and medial temporal lobe T2 signal changes.Neurology. 2011 Apr 19;76(16):1435-6. doi: 10.1212/WNL.0b013e318216eb5f. Neurology. 2011. PMID: 21502605 Free PMC article. No abstract available.
-
Neuroimaging of rapidly progressive dementias, part 1: neurodegenerative etiologies.AJNR Am J Neuroradiol. 2014 Mar;35(3):418-23. doi: 10.3174/ajnr.A3454. Epub 2013 Feb 22. AJNR Am J Neuroradiol. 2014. PMID: 23436051 Free PMC article. Review.
References
-
- Aoki M, Abe K, Oda N, et al. A presenilin-1 mutation in a Japanese family with Alzheimer’s disease and distinctive abnormalities on cranial MRI. Neurology 1997;48:1118–1120 - PubMed
-
- O’Riordan S, McMonagle P, Janssen JC, et al. Presenilin-1 mutation (E280G), spastic paraparesis, and cranial MRI white-matter abnormalities. Neurology 2002;59:1108–1110 - PubMed
-
- Mendez MF, Ghajarania M, Perryman KM. Posterior cortical atrophy: clinical characteristics and differences compared to Alzheimer’s disease. Dement Geriatr Cogn Disord 2002;14:33–40 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
