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Review
. 2004 Dec;7(6):778-80.
doi: 10.1016/j.devcel.2004.11.012.

A new cytoskeletal connection for APC: linked to actin through IQGAP

Jennifer S Tirnauer  1
Affiliations
Free article
Review

A new cytoskeletal connection for APC: linked to actin through IQGAP

Jennifer S Tirnauer. Dev Cell. 2004 Dec.
Free article

Abstract

Migrating cells reorganize their actin and microtubule cytoskeletons in response to external cues. In this issue of Developmental Cell, Watanabe et al. now show a molecular connection between the actin crosslinking protein IQGAP1 and the microtubule-stabilizing protein APC that impacts cells' ability to migrate into a wound.

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