Nuclear pore complex structure: unplugged and dynamic pores
- PMID: 15572121
- DOI: 10.1016/j.devcel.2004.11.010
Nuclear pore complex structure: unplugged and dynamic pores
Abstract
Nuclear pore complexes (NPCs) are large protein assemblies embedded in the nuclear envelope that act as passageways for transport of molecules into and out of the nucleus. Two new studies, one in Nature Cell Biology and one in Science , offer direct evidence that the NPC is a highly dynamic structure.
Similar articles
-
Entry into the nuclear pore complex is controlled by a cytoplasmic exclusion zone containing dynamic GLFG-repeat nucleoporin domains.J Cell Sci. 2014 Jan 1;127(Pt 1):124-36. doi: 10.1242/jcs.133272. Epub 2013 Oct 21. J Cell Sci. 2014. PMID: 24144701
-
Functional architecture of the nuclear pore complex.Annu Rev Biophys. 2012;41:557-84. doi: 10.1146/annurev-biophys-050511-102328. Annu Rev Biophys. 2012. PMID: 22577827 Review.
-
Dynamic nuclear pore complexes: life on the edge.Cell. 2006 Jun 16;125(6):1041-53. doi: 10.1016/j.cell.2006.05.027. Cell. 2006. PMID: 16777596 Review.
-
Structural and functional insights into nucleocytoplasmic transport.Histol Histopathol. 2008 Aug;23(8):1025-33. doi: 10.14670/HH-23.1025. Histol Histopathol. 2008. PMID: 18498078 Review.
-
The structure of the nuclear pore complex.Annu Rev Biochem. 2011;80:613-43. doi: 10.1146/annurev-biochem-060109-151030. Annu Rev Biochem. 2011. PMID: 21495847 Review.
Cited by
-
Influenza virus-induced caspase-dependent enlargement of nuclear pores promotes nuclear export of viral ribonucleoprotein complexes.J Virol. 2015 Jun;89(11):6009-21. doi: 10.1128/JVI.03531-14. Epub 2015 Mar 25. J Virol. 2015. PMID: 25810542 Free PMC article.
-
Insights into the nuclear export of murine leukemia virus intron-containing RNA.RNA Biol. 2015;12(9):942-9. doi: 10.1080/15476286.2015.1065375. RNA Biol. 2015. PMID: 26158194 Free PMC article. Review.
-
Cross-talk between snurportin1 subdomains.Mol Biol Cell. 2005 Oct;16(10):4660-71. doi: 10.1091/mbc.e05-04-0316. Epub 2005 Jul 19. Mol Biol Cell. 2005. PMID: 16030253 Free PMC article.
-
Bio-Inspired Multi-Functional Drug Transport Design Concept and Simulations.Bioengineering (Basel). 2017 Apr 25;4(2):37. doi: 10.3390/bioengineering4020037. Bioengineering (Basel). 2017. PMID: 28952516 Free PMC article.
-
Nuclear envelope breakdown is coordinated by both Nup358/RanBP2 and Nup153, two nucleoporins with zinc finger modules.Mol Biol Cell. 2006 Feb;17(2):760-9. doi: 10.1091/mbc.e05-06-0485. Epub 2005 Nov 28. Mol Biol Cell. 2006. PMID: 16314393 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources