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Case Reports
. 2004 Dec;19(12):3180-2.
doi: 10.1093/ndt/gfh436.

Acute renal failure in SARS patients: more than rhabdomyolysis

Vin-Cent Wu  1 , Po-Ren Hsueh, Wei-Chou Lin, Jenq-Wen Huang, Hung-Bin Tsai, Yung-Ming Chen, Kwan-Dun Wu; SARS Research Group of the National Taiwan University College of Medicine and National University Hospital
Affiliations
Case Reports

Acute renal failure in SARS patients: more than rhabdomyolysis

Vin-Cent Wu et al. Nephrol Dial Transplant. 2004 Dec.
No abstract available

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Figures

Fig. 1.
Fig. 1.
(a) The kidney from case 1. The renal tubule showed prominent cytoplasmic wasting pigment deposition with lymphocytes. The casts in the tubules (arrow) are positive for myoglobin (immunohistochemical stain, 200×). (b) The skeletal muscles from case 2. Myoid giant cells (white arrow) and interstitial ecstatic lymphovascular structures with inflammatory cell infiltration are evident (HE stain, 100×). (c) The kidney from case 2. There are several Mallory body-like casts (arrowhead) in dilated lumens with some sloughed and flattened renal tubular epithelial cells, indicating rhabdomyolysis and acute tubular necrosis. Interstitial infiltration of mononuclear cells is evident. There was a mild increase in mesangial cellularity and matrix (HE, 200×). (d) The glomerulus of case 2 (electron microscopy). Intact basement membrane surrounded by podocytes (×11 500). There was no immune complex deposition or virus particles.
See this image and copyright information in PMC

References

    1. Tsai HB, Huang JW, Chen KY et al Acute renal failure and renal replacement therapy in SARS patients. Presented at the Annual Committee on American Society of Nephrology, San Diego, November 12–17, 2003. [abstract]
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    1. Tsai HB, Huang JW, Wu VC et al. Serum creatine phosphokinase predict the clinical outcome in SARS patients. Presented at the 20th Annual Committee on Taiwan Society of Nephrology, Taipei, December 13–14, 2003. [abstract]
    1. Hsueh PR, Chen PJ, Hsiao CH et al Patient data, early SARS epidemic, Taiwan. Emerg Infect Dis 2004; 10: 489–493 - PubMed
    1. Nicholls JM, Poon LL, Lee KC et al Lung pathology of fatal severe acute respiratory syndrome. Lancet 2003; 361: 1773–1778 - PMC - PubMed

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