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Review
. 2004 Oct;43(10):931-4.
doi: 10.2169/internalmedicine.43.931.

Renal transplant recipient with chronic hepatitis C who obtained sustained viral response after interferon-beta therapy

Ichiro Konishi  1 , Norio Horiike, Kojiro Michitaka, Nobuko Ochi, Shinya Furukawa, Hisaka Minami, Morikazu Onji
Affiliations
Free article
Review

Renal transplant recipient with chronic hepatitis C who obtained sustained viral response after interferon-beta therapy

Ichiro Konishi et al. Intern Med. 2004 Oct.
Free article

Abstract

A 44-year-old Japanese woman with a history of living-related renal transplantation was treated with interferon-beta (IFN-beta) for chronic infection with sero-group 2 hepatitis C virus (HCV). Serum HCV-RNA titer was 160 kilo-international units/ml. Treatment with intravenous IFN-beta daily was given for 6 weeks. Serum HCV-RNA was undetectable at 3 weeks after initiating therapy. Renal graft rejection did not occur. Six months after completing therapy, she obtained sustained viral response. This case demonstrates that IFN-beta therapy safely induced clearance of HCV in a renal transplant recipient with stable renal function, low viral load and/or HCV sero-group 2.

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