[Contribution of bone quality to fracture risk]

Abstract

Recently Bone quality has been recognized as an important contributing factor of bone strength, as clearly stated in NIH (National Institute of Health) consensus development panel of 2000 that bone strength reflects both bone density and bone quality. Bone quality refers to architecture, turnover, damage accumulation, mineralization and matrix. In the treatment of osteoporosis anti-resorptive agents increase bone strength with decreasing bone turnover. It is important to control bone turnover within favorable range to increase bone strength without deterioration of bone quality.