doi: 10.1248/cpb.52.1483.
Two new lactones and one new aryl-8-oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia sophia
Affiliations
- PMID: 15577251
- DOI: 10.1248/cpb.52.1483
Item in Clipboard
Two new lactones and one new aryl-8-oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia sophia
Chem Pharm Bull (Tokyo).
2004 Dec.
Free article
Abstract
Two new lactones (1, 2), descurainolide A and B, and one new aryl-8-oxa-bicyclo[3,2,1]-oct-3-en-2-one (3), descurainin, together with five known compounds (4-8), were isolated from the seeds of Descurainia sophia (L.) WEBB ex PRANTL. The structures of the new compounds were elucidated by extensive studies of their 1D, 2D NMR and HR-MS. Compounds 4 and 5 showed cytotoxicity.
Similar articles
-
A novel sulphur glycoside from the seeds of Descurainia sophia (L.).J Asian Nat Prod Res. 2005 Dec;7(6):853-6. doi: 10.1080/1028602042000204072. J Asian Nat Prod Res. 2005. PMID: 16308204
-
Two new compounds from the seeds of Descurainia sophia.Pharmazie. 2005 Sep;60(9):717-8. Pharmazie. 2005. PMID: 16222879
-
Cytotoxic styryl-lactones from the leaves and twigs of Polyalthia crassa.J Nat Prod. 2006 Dec;69(12):1728-33. doi: 10.1021/np060323u. J Nat Prod. 2006. PMID: 17190450
-
Therapeutic effects and mechanisms of actions of Descurainia sophia.Int J Med Sci. 2020 Aug 1;17(14):2163-2170. doi: 10.7150/ijms.47357. eCollection 2020. Int J Med Sci. 2020. PMID: 32922177 Free PMC article. Review.
-
Strategies for the synthesis of the novel antitumor agent peloruside A.Curr Opin Drug Discov Devel. 2008 Mar;11(2):251-71. Curr Opin Drug Discov Devel. 2008. PMID: 18283613 Free PMC article. Review.
Cited by
-
Flixweed vs. Polyethylene Glycol in the Treatment of Childhood Functional Constipation: A Randomized Clinical Trial.Iran J Pediatr. 2015 Apr;25(2):e425. doi: 10.5812/ijp.425. Epub 2015 Apr 18. Iran J Pediatr. 2015. PMID: 26196006 Free PMC article.
-
Optimization of supercritical fluid extraction of essential oils and fatty acids from flixweed (Descurainia Sophia L.) seed using response surface methodology and central composite design.J Food Sci Technol. 2015 Jul;52(7):4450-8. doi: 10.1007/s13197-014-1353-3. Epub 2015 Mar 7. J Food Sci Technol. 2015. PMID: 26139911 Free PMC article.
-
Lepidiumuridine A: A New Natural Uridine Derivative as a Phytoestrogen Isolated from the Seeds of Lepidium apetalum Willd.Evid Based Complement Alternat Med. 2018 Sep 4;2018:2813465. doi: 10.1155/2018/2813465. eCollection 2018. Evid Based Complement Alternat Med. 2018. PMID: 30254685 Free PMC article.
-
Searching for synergistic bronchodilators and novel therapeutic regimens for chronic lung diseases from a traditional Chinese medicine, Qingfei Xiaoyan Wan.PLoS One. 2014 Nov 14;9(11):e113104. doi: 10.1371/journal.pone.0113104. eCollection 2014. PLoS One. 2014. PMID: 25397687 Free PMC article.
-
Ethanolic extract of Descurainia sophia seeds sensitizes A549 human lung cancer cells to TRAIL cytotoxicity by upregulating death receptors.BMC Complement Altern Med. 2016 Apr 2;16:115. doi: 10.1186/s12906-016-1094-0. BMC Complement Altern Med. 2016. PMID: 27039295 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
