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Comparative Study
. 2004 Dec;17(3-6):313-6.
doi: 10.1007/s10334-004-0067-3. Epub 2004 Dec 1.

Vessel size imaging using low intravascular contrast agent concentrations

I Troprès  1 , L Lamalle, R Farion, C Segebarth, C Rémy
Affiliations
Comparative Study

Vessel size imaging using low intravascular contrast agent concentrations

I Troprès et al. MAGMA. 2004 Dec.

Abstract

Vessel size index (VSI) measurements have been validated on rats bearing a glioma with high doses of contrast agent. The aim of this study was to evaluate the impact of using a reduced dose of contrast agent, necessary for clinical trials. Experiments were performed on rats at three doses of AMI-227 and clearly show higher VSI values at lower doses, whatever the region of interest (contralateral, peritumoral and intratumoral tissue). These results are in good correlation with Monte-Carlo simulations on healthy brain and suggest that only relative values can be obtained at clinical contrast agent doses and magnetic fields.

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References

    1. Magn Reson Med. 1999 Mar;41(3):499-509 - PubMed
    1. Magn Reson Med. 2000 Jun;43(6):845-53 - PubMed
    1. Magn Reson Med. 2004 Mar;51(3):533-41 - PubMed
    1. Magn Reson Med. 1998 Dec;40(6):793-9 - PubMed
    1. NMR Biomed. 1995 Nov-Dec;8(7-8):345-58 - PubMed

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