Vitamin D requirements during pregnancy
- PMID: 15585798
- DOI: 10.1093/ajcn/80.6.1740S
Vitamin D requirements during pregnancy
Abstract
Adequate vitamin D concentrations during pregnancy are necessary to ensure appropriate maternal responses to the calcium demands of the fetus and neonatal handling of calcium. The purpose of this report is to review studies that investigated maternal and neonatal outcomes of vitamin D deficiency or supplementation during pregnancy. Most studies reported included women at high risk of vitamin D deficiency, because of low vitamin D and calcium intake or decreased ability to synthesize endogenous vitamin D (attributable to lack of sun exposure or to heavily pigmented skin). Overall, vitamin D supplementation in these populations leads to improved neonatal handling of calcium. Results concerning benefits for fetal growth and bone development are inconclusive. There is no evidence of a benefit of supplementation during pregnancy above amounts routinely required to prevent vitamin D deficiency.
Comment in
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Vitamin D deficiency during pregnancy: a risk factor not only for fetal growth and bone metabolism but also for correct development of the fetal immune system?Am J Clin Nutr. 2005 May;81(5):1177; author reply 1177-8. doi: 10.1093/ajcn/81.5.1177. Am J Clin Nutr. 2005. PMID: 15883446 No abstract available.
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