The polymorphism of the genes/enzymes involved in the last two reductive steps of monolignol synthesis: what is the functional significance?

Abstract

The polymorphism of genes and enzymes involved in the last two steps of monolignol synthesis is examined in the light of recent data coming from genomic studies and mutant/transformant analyses. The two catalytic activities considered--cinnamoyl-CoA reductase (CCR) and cinnamyl alcohol dehydrogenase (CAD)--are encoded by small multigene families. While some degree of diversification can be noted at the sequence level, it is often difficult to use this information to assign substrate specificities to each member of a gene family. Expression profiles, however, suggest for both CAD and CCR the existence of two sub-families: one devoted to developmental lignification, and the other involved in the synthesis of defence-related compounds.