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. 2004 Dec;364(9451):2142-51.
doi: 10.1016/S0140-6736(04)17556-9.

Exceptional matters

Affiliations

Exceptional matters

Keith Peters. Lancet. 2004 Dec.
No abstract available

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Figures

Figure 1
Figure 1
Semilogarithmic plot of fraction of cases of retinoblastoma not yet diagnosed against age in months Unilateral and bilateral separately plotted. Kinetics of bilateral cases indicate “one hit”, whereas kinetics of the unilateral cases indicate “two hits”. Reprinted from reference 3 with permission of Alfred G Knudson.
Figure 2
Figure 2
Electron microscopy showing molecular aggregates of mutated alpha-1 antritrypsin molecules in hepatocytes Reprinted from reference 16 with permission of National Academy of Sciences, USA (copyright 1994).
Figure 3
Figure 3
Four chains of poly-L-glutamine linked by hydrogen bonds between their main chain and side-chain amides Reprinted from reference 24 with permission of Elsevier.
Figure 4
Figure 4
Effects of recombinant leptin in children with total deficiency of leptin Weights of three children compared with normal centiles for girls (upper) and boys (middle and lower). Arrows indicate start of treatments. (B) Child B before (left) and after (right) treatment. Reprinted from reference 46 with permission of the American Society of Clinical Investigation.
Figure 5
Figure 5
Effects of leptin on assays of cell mediated immunity (A) proliferation assays and (B) cytokines interferon γ, interleukin 4, interleukin 10, and transforming growth factor β. Leptin therapy reverses the T-cell hyporesponsiveness. Reprinted from reference 46 with permission of the American Society of Clinical Investigation.
Figure 6
Figure 6
Effect of plasma exchange and immunosuppression on anti-GBM antibody and renal function Autoantibody production ceased and never recurred. Reprinted from reference 51 with permission of the BMJ Publishing Group.
Figure 7
Figure 7
Effect of plasma exchange in a patient with myasthenia gravis Improvement in neuromuscular function is dramatic. VC=vital capacity. Reprinted from reference 53 with permission.

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