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Review
. 2005 Jan;96(1):235-40.
doi: 10.1016/j.ygyno.2004.09.023.

Long natural history of recurrent granulosa cell tumor of the ovary 23 years after initial diagnosis: a case report and review of the literature

Katherine D Crew  1 , Michael H Cohen, Daniel H Smith, Amy D Tiersten, Nikki M Feirt, Dawn L Hershman
Affiliations
Review

Long natural history of recurrent granulosa cell tumor of the ovary 23 years after initial diagnosis: a case report and review of the literature

Katherine D Crew et al. Gynecol Oncol. 2005 Jan.

Abstract

Background: Granulosa cell tumors (GCTs) of the ovary are rare, hormonally active neoplasms characterized by endocrine manifestations, an indolent course, and late relapse.

Case: We report a case of a prolonged history of ovarian GCT managed primarily with repeat surgical resections.

Conclusion: This case illustrates the benefits of cytoreductive surgery for the management of recurrent disease, the use of serum tumor markers to help guide therapy, and the importance of extended follow-up.

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