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. 2004 Nov;41(11):1129-32.

Linezolid

Affiliations
  • PMID: 15591662
Free article

Linezolid

Manish Narang et al. Indian Pediatr. 2004 Nov.
Free article

Abstract

Linezolid is an oxazolidinone antibacterial agent that acts by inhibiting the initiation of bacterial protein synthesis. Linezolid has a wide spectrum of activity against gram-positive organisms including methicillin resistant staphylococci, penicillin resistant pneumococci and vancomycin resistant enterococcus faecalis and E. faecium. Linezolid has a good bio-availability orally and could be switched from parenteral to oral therapy while treating serious infections. Linezolid is well tolerated in children.

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