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. 2005 Jan 1;191(1):122-6.
doi: 10.1086/426451. Epub 2004 Dec 6.

Detection of Pneumocystis carinii f. sp. hominis and viruses in presumably immunocompetent infants who died in the hospital or in the community

Sergio L Vargas  1 , Carolina A Ponce, Vivian Luchsinger, Cecilia Silva, Myriam Gallo, René López, José Belletti, Luis Velozo, Ricardo Avila, Maria A Palomino, Samuel Benveniste, Luis F Avendaño
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Detection of Pneumocystis carinii f. sp. hominis and viruses in presumably immunocompetent infants who died in the hospital or in the community

Sergio L Vargas et al. J Infect Dis. .

Abstract

Fresh-frozen lung and tracheal-aspirate specimens obtained from 112 infants who died in Santiago, Chile, during 1998-2000 were analyzed for the presence of Pneumocystis DNA, by use of nested DNA amplification of the large subunit mitochondrial rRNA, and for the presence of viruses, by use of culture and immunofluorescence. Pneumocystis DNA was detected in specimens from 45 (51.7%) of 87 infants who died in the community and from 5 (20%) of 25 infants who died in the hospital (P=.006). Primary infection with Pneumocystis was highly frequent among infants who die unexpectedly in the community. Infection with viruses was more common in infants who died in the hospital.

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