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Review
. 2005 Jan;20(1):5-9.
doi: 10.1007/s00467-004-1681-z. Epub 2004 Nov 25.

The clinical trial imperative

Debbie Gipson, Howard Trachtman
Review

The clinical trial imperative

Debbie Gipson et al. Pediatr Nephrol. 2005 Jan.

Abstract

As clinical judgment has joined forces with evidence-based medicine, nephrologists critically assess the validity of the data available to support therapeutic decisions for children with kidney disease. Unfortunately, a paucity of data often prevents the practice of evidence-based medicine. Three scenarios illustrating the status of evidence and clinical decision making are provided. A review of the pediatric nephrology literature supports a call for general support of ongoing clinical trials and encourages the creation of additional feasible clinical trials to improve the practice of medicine.

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