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Case Reports
. 2004 Sep 2;122(5):217-9.
doi: 10.1590/S1516-31802004000500008.

Inflammatory pseudotumor of the spleen concomitant with renal cell carcinoma: case report

Sérgio Ossamu Loshii  1 , Danielle Giacometti Sakamoto, Tiago Noguchi Machuca, Ryuichi Yatani
Affiliations
Case Reports

Inflammatory pseudotumor of the spleen concomitant with renal cell carcinoma: case report

Sérgio Ossamu Loshii et al. Sao Paulo Med J. .

Abstract
in English, Portuguese

Context: Inflammatory pseudotumor is a rare benign lesion that can occur at a wide variety of primary sites. It is usually worrisome for the patient and the medical staff, since it cannot be clinically or radiologically distinguished from malignant entities.

Case report: We report on a case of splenic inflammatory pseudotumor presenting with concomitant renal cell carcinoma. Despite the alarming macroscopic appearance of pseudotumors, their microscopic features usually confirm the inflammatory nature of such lesions. Evidence regarding the etiology of pseudotumors is still lacking, but hypotheses have been created.

CONTEXTO:: Pseudotumor inflamatório é uma lesão benigna rara que pode se desenvolver em uma grande variedade de órgãos. Sua grande importância na prática médica reside na enorme dificuldade de distingui-lo tanto clinicamente quanto radiologicamente de condições malignas.

RELATO DE CASO:: Os autores relatam um caso de pseudotumor envolvendo o baço e apresentandose concomitantemente a um carcinoma renal de células claras. Apesar da semelhança macroscópica a tumores malignos, as características inflamatórias do pseudotumor são facilmente evidenciadas à microscopia. Apesar de hipóteses terem sido formuladas, os mecanismos patogenéticos relacionados ao pseudotumor ainda não estão bem estabelecidos.

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Conflict of interest statement

Conflict of interest: None.

Figures

Figure 1
Figure 1. Computerized tomography displaying a lobulated splenic mass suggestive of a metastatic malignancy in a 66-year-old man.
Figure 2
Figure 2. Photomicrography showing fibroblasts and lymphocytes of benign appearance, thus confirming the inflammatory nature of the tumor (hematoxylin-eosin, 200 x).
See this image and copyright information in PMC

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